A CENTURY OF INNOVATION
Japanese Skincare Science For Visibly Even, Radiant Skin. Twenty Years In The Making.
For more than twenty years, Otsuka studied how to support healthy-looking skin’s natural renewal and a more even, radiant-looking tone. Sakuraé brings that research, born of a century of Japanese science, to the U.S. for the first time.
Healthy skin is beautiful skin.
Skin looks more radiant when its natural renewal is working well. Rather than focusing on surface correction alone, Sakuraé is designed to support that healthy-looking skin renewal, for more even-toned skin over time.
Founded in Japan in 1921, Otsuka spent decades developing a philosophy rooted in precision, discipline, and long-term research. In 1990, that scientific approach expanded into skincare.


In 2002, Otsuka Pharmaceutical began researching a different approach to visibly uneven skin: could one serum support both visible tone balance and healthy-looking skin renewal over time? Sakuraé is the answer.
Our Double Action Serum brings AMP, the healthy-looking skin renewal engine, and LVC, the tone regulator, together: a dual-action approach for a more radiant, clearer skin.

The journey from 1921 to your skin.
The journey from 1921 to your skin.
Why Sakuraé?
Pharmaceutical Heritage
Built on a century of Otsuka Japanese Science.
RECOGNIZED IN JAPAN
A top-rated pick from LDK Ageless, a leading independent consumer-testing publication.
Proprietary AMP Formula
An Otsuka-exclusive compound, refined over two decades of research.
TWO BENEFITS. ONE SERUM
AMP supports healthy-looking skin renewal while LVC helps even tone
The Name
Sakuraé. The light that was always there.

Sakuraé takes its name from "Sakura No Kasane". A Japanese tradition inspired by the soft layering of cherry blossom hues. A philosophy of beauty through balance, subtlety, and precision, now translated into skincare through healthy-looking, luminous skin.
Your Questions, Answered.
Otsuka is a Japanese Group founded in Tokushima in 1921, with more than a century of science behind it. Sakuraé was developed within Otsuka, bringing that same discipline of precision and long-term science to skincare.
A century of pharmaceutical science. Twenty years of Research. Fourteen days to experience it.
*Free with subscription for new customers. Pay only shipping. Cancel anytime.





